What is the mechanisms of obesity
obesity - - Posted on June, 28 at 3:02 am
No ne can say that obese people is someone who eats too. Some eat more scarce that many obese. For that obesity appears, main cause for obesity is genetic factors and lack of natural regulation of appetite on energy costs, or an overflow of this regulation by an eating disorder, in the form of excess voluntary or compulsive.
It is now demonstrated that obesity gained result of a bad dialogue between the brain and fat cells. The appetite centres located in the hypothalamus (the base of the brain) receive a wealth of information from the stomach (fullness with meals), intestine (presence of nutrients), blood (rate glucose), which are used to adjust the volume of food. They are especially chemical messages from fat cells, which help regulate appetite in the long term. Obesity occurs when the dialogue is disrupted by poor quality of information or an inability of the brain to collect them. pharmacokinetic drugs mainly used for preventing diabetes and insulin obesity
Leptin is the messenger best known, but two other hormones, such as leptin, the appetite control have been discovered recently: ghreline and resistin.
If the obesity gene is faulty and that the rate remains low leptin or that leptin produced is of poor quality, appetite remains uncontrolled.
– The ghreline: isolated in 1999 in the stomach and intestine, ghreline also acts on the hypothalamus to stimulate the appetite and fat storage. The syndrome Prader-Willi is a rare genetic disease in which the rate of ghreline is abnormally high, it causes a massive obesity in young children.
– The resistin: isolated in 2001, this hormone is secreted by fat cells as leptin. Its rate is high in obesity and type II diabetes. Its normal function is to stabilize blood sugar on an empty stomach. In his absence, the blood sugar decreases, causing a sensation of hunger.
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